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RecruitingNot ApplicableNCT07276152

Plasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation Technology

Plasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation Technology vs Unaugmented Control Music in Healthy Controls and Patients With AVP-Deficiency

Sponsor

University Hospital, Basel, Switzerland

Enrollment

22 participants

Start Date

Jan 9, 2026

Study Type

INTERVENTIONAL

Conditions

Sonic Augmentation Technology

Summary

The investigator aim to investigate wheather music modified by sonic augmentation technology can produce increasing oxytocin levels with minimal to no side effects in a highly standardized setting

Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Part 1:
  • Adult healthy controls
  • No medication, except hormonal contraception
  • Confirmed diagnosis of AVP-Deficiency
  • Age ≥ 18 years

Exclusion Criteria15

  • Participation in a trial with investigational drugs within 30 days
  • Illicit substance use (except for cannabis) more than 10 times in lifetime or any time within the previous two months
  • Consumption of alcoholic beverages \>15 drinks/week
  • Tobacco smoking \>10 cigarettes/day
  • Current or previous major psychiatric disorder (e.g., major depression, schizophrenia spectrum disorder)
  • Psychotic disorder in first-degree relatives
  • Pregnancy and breastfeeding
  • Part 2:
  • Participation in a trial with investigational drugs within 30 days
  • Illicit substance use (except for cannabis) more than 10 times in lifetime or any time within the previous two months
  • Consumption of alcoholic beverages \>15 drinks/week
  • Tobacco smoking \>10 cigarettes/day
  • Current or previous major psychiatric disorder (e.g., major depression, schizophrenia spectrum disorder)
  • Psychotic disorder in first-degree relatives
  • Pregnancy and breastfeeding
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Interventions

OTHERsonic augmentation technology

Participants/ patients listen to music enhanced with sonic aumentation technology

Locations(1)

University Hospital Basel

Basel, Switzerland

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NCT07276152