RecruitingNot ApplicableNCT07279441

Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints


Sponsor

NYU Langone Health

Enrollment

460 participants

Start Date

Jan 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study examines how cochlear implant users understand and comprehend speech in realistic communication situations. Through six experiments measuring listening effort via pupillometry and discourse comprehension, we will investigate how linguistic context, cognitive demands, and processing time affect speech understanding in CI users, and in normal-hearing controls) to identify factors underlying communication resilience versus vulnerability and develop improved, ecologically valid assessment and rehabilitation strategies.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Experiment 1: Syntactic and Semantic Context, a behavioral approach called Experiment 2: False Hearing and Context Overuse, and others for people with cochlear implant users. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExperiment 1: Syntactic and Semantic Context

* Recall of meaningful sentences, anomalous word strings, and unstructured word lists * Measurement of syntactic and semantic gain * Pupillometry during auditory and visual presentation

BEHAVIORALExperiment 2: False Hearing and Context Overuse

* Two-choice word recognition task with semantic priming/luring in multi-talker babble * Three Signal-to-Noise Ratio (SNR) levels (heavy, medium, light noise) * Confidence ratings for responses * Pupillometry measurement

BEHAVIORALExperiment 3: Two-Sentence Problem

* Speech recognition and recall of single sentences vs. paired sentences * Manipulation of inter-sentence semantic predictability (high vs. low) * Four test conditions: 1-sentence, 2-sentences, 2-sentences+pre-prompt, 2-sentences+post-prompt * Pupillometry during task

BEHAVIORALExperiment 4: Cascading Effects on Discourse Comprehension

* Recall of 27 narrative passages (67-97 words each) * Propositional analysis scoring (main ideas, mid-level ideas, details) * Measurement of semantic hierarchy effect * Pupillometry during listening

BEHAVIORALExperiment 5: Self-Paced Discourse Comprehension

* 24 discourse passages (150 words each): 12 narrative, 12 expository * Continuous presentation vs. self-paced presentation (stops at clause/sentence boundaries) * Measurement of pause times and comprehension recall * Pupillometry during task

BEHAVIORALExperiment 6: Clinical Application

* Self-Paced Sentence Comprehension * Sentences with varying syntactic complexity (active-conjoined, subject-relative, object-relative) * Continuous vs. self-paced (with pause at major clause boundary) presentation * True/false comprehension verification statements * Pupillometry measurement


Locations(2)

Brandeis University

Waltham, Massachusetts, United States

NYU Langone Health

New York, New York, United States

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NCT07279441


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