RecruitingNCT07283042

Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta Spectrum

Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta


Sponsor

University of California, Los Angeles

Enrollment

60 participants

Start Date

Dec 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study evaluates the clinical implementation of intra-operative topographic classification system for PAS. In addition to a standard of care risk stratification prenatal ultrasound for patients with a risk of PAS, this study adds an additional intraoperative surgical staging protocol to validate the classification system, improve surgical approach, and significantly clinical outcomes of pregnant people with an a prior risk of PAS. The study will involve pregnant patients with PAS risk factor, include data collection spanning prenatal assessment, intraoperative classification, surgical technique implementation and postoperative analysis. The anticipated study duration is approximately 36-48 months.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Modified subtotal hysterectomy, a procedure called One-Step Conservative Surgery, and others for people with placenta accreta. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURETotal Hysterectomy

Removal of entire uterus

PROCEDUREModified subtotal hysterectomy

When partial tissue integrity is preserved

PROCEDUREOne-Step Conservative Surgery

Considered when significant healthy myometrium is preserved


Locations(1)

University of California, Los Angeles

Los Angeles, California, United States

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NCT07283042


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