Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta Spectrum
Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta
University of California, Los Angeles
60 participants
Dec 1, 2025
OBSERVATIONAL
Conditions
Summary
This study evaluates the clinical implementation of intra-operative topographic classification system for PAS. In addition to a standard of care risk stratification prenatal ultrasound for patients with a risk of PAS, this study adds an additional intraoperative surgical staging protocol to validate the classification system, improve surgical approach, and significantly clinical outcomes of pregnant people with an a prior risk of PAS. The study will involve pregnant patients with PAS risk factor, include data collection spanning prenatal assessment, intraoperative classification, surgical technique implementation and postoperative analysis. The anticipated study duration is approximately 36-48 months.
Eligibility
Inclusion Criteria6
- Pregnant people suspected of having PAS based on ultrasound findings or clinical risk factors
- Patients undergoing planned surgical intervention for PAS, including a planned cesarean
- Individuals who provide informed consent to participate in the study
- Patients with at least one prenatal assessment before surgery
- Expected age range: 18-55
- Patient has agreed to conservative management approach as part of standard of care if feasible intraoperatively
Exclusion Criteria2
- Patients who decline participation or withdraw consent
- Those with contraindications to the planned surgical procedure
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Interventions
Removal of entire uterus
When partial tissue integrity is preserved
Considered when significant healthy myometrium is preserved
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07283042