Phase II Trial of Albumin-Bound Paclitaxel Combined With Nedaplatin (TP) Via Hepatic Arterial Infusion for Advanced Breast Cancer Patients With Liver Metastases After Failure of Standard Therapy

This trial is testing a chemotherapy combination — albumin-bound paclitaxel and nedaplatin — delivered directly into the liver's blood supply (hepatic arterial infusion) for breast cancer patients whose cancer has spread to the liver and has stopped responding to standard treatments. **You may be eligible if...** - Your breast cancer has spread to the liver, confirmed by biopsy or imaging - The cancer is only in your liver (no other organ involvement) - You have already tried at least 2 standard treatments (such as hormone therapy, chemotherapy, or targeted therapy) without success - You are between 18 and 70 years old - You are able to care for yourself and perform daily activities (ECOG performance status 0–2) **You may NOT be eligible if...** - Your cancer has spread to organs other than the liver - You have not yet tried at least two prior treatments - You are older than 70 or younger than 18 - Your general health is significantly impaired Talk to your doctor to see if this trial is right for you.