RecruitingNCT07287761

Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting

Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting: A Prospective, Observational Study


Sponsor

Ankara Education and Research Hospital

Enrollment

60 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Coronary Artery Bypass Grafting (CABG) is a common surgical procedure for ischemic heart disease, but it often leads to severe acute and chronic postoperative pain, which can delay recovery and reduce patient comfort. Effective pain management is crucial to prevent pulmonary complications and long hospital stays. Peripheral nerve blocks are increasingly used to reduce opioid consumption and improve patient satisfaction after major surgery. This prospective, observational study aims to compare the effectiveness and safety of two different regional anesthesia techniques, the Erector Spinae Plane Block (ESPB) and the Serratus Posterior Superior Intercostal Plane Block (SPSIPB), in managing postoperative pain in patients undergoing CABG via median sternotomy. Patients aged 18-80 years, classified as ASA II-III, who are scheduled for elective CABG will be included. The choice of block technique (ESPB or SPSIPB) will be determined by the operating anesthesiologist based on the visibility of anatomical structures (transverse processes) under ultrasound guidance. All patients will receive the same general anesthesia and be managed postoperatively with Intravenous Patient-Controlled Analgesia (PCA). The main goal is to determine which block provides optimal pain control, measured by the time to first rescue analgesia and pain scores (NRS) at various time points after extubation. Secondary outcomes include intraoperative opioid consumption, total PCA usage, extubation time, and the incidence of opioid-related side effects. The findings will help optimize pain protocols for cardiac surgery patients.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • Patients scheduled for elective Coronary Artery Bypass Grafting (CABG) via median sternotomy.
  • Age between 18 and 80 years.
  • Classification of American Society of Anesthesiologists (ASA) Physical Status Class II or III.
  • Patients who provide written and verbal informed consent to participate in the study.

Exclusion Criteria11

  • Patients who do not provide consent.
  • Age older than 80 years or ASA Physical Status Class > III.
  • Patients who do not understand the Numerical Rating Scale (NRS) or have communication difficulties.
  • Patients with a known history of coagulation disorders or bleeding disorders.
  • Patients with skin infection at the site of peripheral nerve block application.
  • Patients with Morbid Obesity (Body Mass Index BMI>35 kg/m2).
  • Patients with chronic pain, opioid or substance dependence, or who use chronic analgesics.
  • Patients with known allergy to local anesthetics.
  • Patients with liver or kidney function disorders.
  • Patients with a history of previous median sternotomy operation.
  • Patients undergoing emergency surgery.

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Locations(1)

Ankara Training and Research Hospital

Ankara, Altındag, Turkey (Türkiye)

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NCT07287761


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