A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Obstructive Pulmonary Disease (COPD)

This trial is testing a new inhaled drug called BBT002 in healthy volunteers (Part A) and in people with moderate COPD — a chronic lung disease that makes breathing difficult (Part B) — to evaluate its safety and how it works in the body. **You may be eligible if...** - You are between 18 and 65 years old (healthy volunteers) or 35 and 75 years old (COPD patients) - Your BMI is between 18 and 32 kg/m² and you weigh under 120 kg - For COPD patients: you have a confirmed COPD diagnosis with moderate airflow limitation on breathing tests (FEV1 50–80% predicted) - You are a non-smoker, light smoker (up to 5 cigarettes/day), or ex-smoker - You are using adequate contraception if of childbearing potential **You may NOT be eligible if...** - You have HIV, hepatitis B or C - Your lung function is below 50% or above 80% predicted (for COPD group) - You have significant other illnesses - You have a positive pregnancy test Talk to your doctor to see if this trial is right for you.