RecruitingNot ApplicableNCT07291245

Kawasaki MATCH Trial

Kawasaki MATCH: A Clinical Decision Support Tool to Detect KD


Sponsor

University of California, San Diego

Enrollment

200 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Evaluating the impact of a machine-learning clinical decision support tool on provider practice when evaluating febrile patients with Kawasaki Disease (KD) and non-KD illnesses.


Eligibility

Min Age: 30 DaysMax Age: 17 Years

Inclusion Criteria10

  • Measured or subjective fever for \>= 3 calendar days
  • One measured fever \>= 38.0 C (home or in ED)
  • One or more clinical feature of Kawasaki Disease including:
  • Rash
  • Conjunctival injection
  • Oropharyngeal changes
  • Extremity changes (erythema, edema, desquamation)
  • Cervical adenopathy (\>=1.5cm)
  • Infants \< 6 months of age with \>= 7 days of fever eligible even if none of the above clinical features
  • Requires IV/phlebotomy for clinical evaluation

Exclusion Criteria3

  • Congenital or Acquired Immune function
  • Genetic disorders
  • Current systemic steroid, immunosuppression, or chemotherapy treatment (not including inhaled steroids)

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Interventions

OTHERKawasaki MATCH

Providers access the Kawasaki MATCH decision support tool. Patient information is entered into the tool and a risk score is indicated to the provider. Kawasaki MATCH is a previously validated machine-learning decision support tool for the diagnosis of Kawasaki Disease. This tool utilizes patient age, 18 laboratory features, and 5 clinical features to formulate a risk score.


Locations(1)

Rady Children's Hospital, San Diego

San Diego, California, United States

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NCT07291245


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