Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy
Second Affiliated Hospital, School of Medicine, Zhejiang University
330 participants
Jan 6, 2026
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to learn about the long-term prognostic of coronary microvascular dysfuction in Patients with Dilated Cardiomyopathy. The main question it aims to answer is: Does the coronary microvascular dysfunction impact the outcomes in Patients with Dilated Cardiomyopathy.
Eligibility
Inclusion Criteria3
- Dilated cardiomyopathy comfirmed by echocardiography: LVDd \> 55 mm in men or \> 50 mm in women.
- Clinically evident congestive heart failure: Compatible symptoms and signs, and BNP ≥ 35 pg/mL or NT-proBNP ≥ 125 pg/mL, and LV systolic dysfunction defined by LVEF \< 45 %.
- Coronary angiography showing stenosis ≤ 50 % in all major epicardial vessels.
Exclusion Criteria2
- Patients with coronary artery disease, hypertensive heart disease, rheumatic valvular heart disease, myocarditis, and other secondary cardiomyopathies.
- poor angiographic image quality
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Interventions
Patients should undergo coronary angiography to confirm the absence of significant coronary stenosis. Angio-IMR was calculated based on the angiography.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07293338