RecruitingNCT07293559

Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States


Sponsor

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Enrollment

1,150 participants

Start Date

Feb 24, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

IMPAACT 2046/UPLIFT (Understanding Practices of Lactation and Infant Feeding decisions Together with women with HIV) is a multi-site, mixed-methods, observational cohort study. The purpose of the study is to explore infant feeding preferences, practices, and outcomes among mothers with HIV and their families in the United States. It will employ both qualitative and quantitative research methods to address existing knowledge gaps and to understand the clinical, behavioral, and social factors influencing infant feeding decisions. As part of the study's mixed method approach, a longitudinal cohort study of mothers and their infants will be established. The study also aims to pilot a national registry of breastfeeding women living with HIV in the United States.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study explores how women living with HIV think about and experience breastfeeding, to better understand the barriers and decision-making process around infant feeding choices in this population. **You may be eligible if...** - You are a woman living with HIV - You are in one of the following situations: pregnant (28–38 weeks) and considering your feeding options; you gave birth after February 2023 and have not breastfed or have already weaned; or you are currently breastfeeding and plan to wean within the next few months - You are of legal age to provide independent consent **You may NOT be eligible if...** - You do not fall within the eligible pregnancy or postpartum categories defined by the study - You are not able to provide independent informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERNo intervention provided in this study

None; No intervention provided in this study


Locations(11)

University of Southern California (CRS 5048)

Los Angeles, California, United States

David Geffen School of Medicine at UCLA (CRS 5112)

Los Angeles, California, United States

University California, San Diego (CRS 4601)

San Diego, California, United States

University of Colorado, Denver (CRS 5052)

Aurora, Colorado, United States

University of Florida (5051)

Jacksonville, Florida, United States

Univ of Miami Pediatric/Perinatal HIV/AIDS (5127)

Miami, Florida, United States

5030, Emory University School of Medicine Clinical Research Site

Atlanta, Georgia, United States

Lurie Children's Hospital of Chicago (CRS 4001)

Chicago, Illinois, United States

Johns Hopkins University (CRS 5092)

Baltimore, Maryland, United States

Jacobi Med. Ctr. Bronx NICHD CRS (5013)

The Bronx, New York, United States

St. Jude Childrens Research Hosp, Memphis (6501)

Memphis, Tennessee, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07293559


Related Trials