RecruitingPhase 2NCT07294118

Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

Endovascular Infusion of Lidocaine and Steroids in the Middle Meningeal Artery for Pain Management in Spontaneous Subarachnoid Hemorrhage Patients


Sponsor

The University of Texas Medical Branch, Galveston

Enrollment

15 participants

Start Date

Jan 2, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH). It will also study the safety of this treatment.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria3

  • Age ≥18 years.
  • Diagnosed with aneurysmal SAH, Hunt and Hess Grades 1-2.
  • Consent to study procedures and follow-up evaluations.

Exclusion Criteria8

  • Known allergies to lidocaine or steroids.
  • Arteriovenous malformations.
  • Dural Arteriovenous Fistulas.
  • Other significant intracranial pathologies.
  • Hemodynamic instability preventing safe intervention.
  • Previous MMA interventions.
  • Previous craniotomies or need for craniotomy.
  • Need for external ventricular drain.

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Interventions

DRUGLidocaine

The participants will receive 50 mg of lidocaine.

DRUGLidocaine and Dexamethasone

The participants will receive 50 mg of lidocaine and 10 mg of dexamethasone one after the other.


Locations(1)

University of Texas Medical Branch, Galveston

Galveston, Texas, United States

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NCT07294118


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