RecruitingNot ApplicableNCT07295158

Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy Patients: Effect of Sevoflurane vs. Desflurane on Mechanical Power - A Prospective, Randomized, Controlled Trial

Sponsor

Konya City Hospital

Enrollment

138 participants

Start Date

Mar 9, 2026

Study Type

INTERVENTIONAL

Conditions

Perioperative Respiratory Mechanics

Summary

This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Desflurane and a drug called Sevoflurane for people with perioperative respiratory mechanics. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSevoflurane

General anesthesia will be maintained with sevoflurane at 2% concentration in patients assigned to the Sevoflurane Group (Group S). Standardized ventilator settings will be applied for all participants, and mechanical power will be measured at three intraoperative time points while sevoflurane is used as the sole maintenance inhalational agent.

DRUGDesflurane

Maintenance of general anesthesia with desflurane 6% during laparoscopic cholecystectomy. Mechanical power is measured at three intraoperative time points using standardized ventilator settings.

Locations(1)

Konya City Hospital

Konya, Konya, Turkey (Türkiye)

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NCT07295158