RecruitingNCT07295275

Safety and Efficacy of Transarterial ICG Fluorescence-Guided Laparoscopic Anatomical Liver Resection

Safety and Efficacy of Trans-arterial Versus Trans-portal ICG Fluorescence-Guided Laparoscopic Liver Watershed Resection: A Multicenter, Ambispective Cohort Study

Sponsor

West China Hospital

Enrollment

200 participants

Start Date

Mar 1, 2026

Study Type

OBSERVATIONAL

Conditions

Liver Cancer

Summary

This multicenter, ambispective cohort study evaluates the safety and efficacy of trans-arterial Indocyanine Green (ICG) fluorescence-guided laparoscopic liver watershed resection for Hepatocellular Carcinoma (HCC). The study aims to compare the outcomes of the trans-arterial ICG staining approach versus the conventional trans-portal (portal vein) ICG staining approach.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study reviews outcomes of patients who had a type of minimally invasive liver surgery guided by a special glowing dye (ICG fluorescence) to help surgeons remove liver cancer more precisely. **You may be eligible if...** - You are between 18 and 80 years old - You were diagnosed with liver cancer (hepatocellular carcinoma) after surgery - You had laparoscopic (minimally invasive) liver surgery using ICG fluorescence guidance - You have relatively good liver function (Child-Pugh A or B) - You were in good physical condition before surgery **You may NOT be eligible if...** - Your cancer has spread into major blood vessels or bile ducts - You had open (non-laparoscopic) surgery - Your liver function was severely impaired before surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURELaparoscopic Anatomical Liver Resection (guided by transarterial injection of ICG)

Laparoscopic liver resection using ICG fluorescence imaging for tumor and liver segment visualization. Comparison lies in the route of ICG administration (Arterial vs. Portal).