Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics

This study tests whether adding a slow-release antibiotic called Arestin (minocycline microspheres) to standard dental cleaning treatment improves both gum disease and blood sugar control in people with type 2 diabetes and moderate-to-severe periodontitis (gum disease). **You may be eligible if...** - You are 18 or older - You have type 2 diabetes with an HbA1c (blood sugar average) between 7% and 9.5% - You have moderate to severe gum disease (deep pockets in at least 6 spots in your mouth) - You have at least 16 teeth - You have not had any gum treatment in the past 6 months **You may NOT be eligible if...** - You are allergic to minocycline or other tetracycline antibiotics - You are pregnant or breastfeeding - You smoke - You have had systemic antibiotic use recently - You have other serious medical conditions that could affect gum healing Talk to your doctor to see if this trial is right for you.