RecruitingNot ApplicableNCT07298785

Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study


Sponsor

University of California, San Francisco

Enrollment

60 participants

Start Date

Jan 27, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study will refine and pilot test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention in a single-arm pilot trial. The study will test the hypothesis that the Peer-led Dynamic Choice HIV Prevention intervention will be feasible and increase biomedical HIV prevention coverage in the 6 months after receipt of the Peer-led DCP intervention compared to the standard of care in the 6 months prior to intervention implementation.


Eligibility

Sex: FEMALEMin Age: 15 Years

Inclusion Criteria4

  • Age \>=18 years or mature or mature minor \>=15 years;
  • Female sex at birth;
  • HIV negative by country-standard testing algorithm
  • Elevated risk of HIV exposure, defined as at least 1 of the following: a) eligible for PrEP based on Uganda Ministry of Health Guidelines; b) exchange of sex for goods or money in last 6 months; or c) work in bar or guesthouse

Exclusion Criteria2

  • Contraindication to country-recommended PrEP regimen per national guidelines
  • Participation in another HIV prevention study

Interventions

OTHERPeer-led Dynamic Choice HIV Prevention (DCP) intervention

The intervention consists of peer mentor training on patient-centered choice counseling and Peer-led DCP services, and will be delivered by the peer mentor with clinician support: 1. HIV prevention product choice with option to switch over time 2. Rapid access to PEP from peer mentor for unplanned exposures 3. Integration of STI testing and treatment 4. Travel kit 5. Phone/SMS contact for peer support


Locations(1)

Infectious Diseases Research Collaboration

Kampala, Uganda

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NCT07298785


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