RecruitingNot ApplicableNCT07299071

Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.

Randomized Controlled Trial Evaluating the Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.


Sponsor

University Hospital, Bordeaux

Enrollment

592 participants

Start Date

Mar 13, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether using AI-assisted colonoscopy detection software (CAD — computer-aided detection) during a screening colonoscopy can reduce the chances of finding advanced precancerous growths (advanced adenomas) when the patient returns for a follow-up colonoscopy 3 years later. **You may be eligible if...** - You are 18 or older - You are having a colonoscopy as part of a cancer screening program (for example, after a positive stool blood test, or due to personal or family history of colorectal cancer or polyps) - You have provided written informed consent - You have health insurance coverage **You may NOT be eligible if...** - Your colonoscopy could not be completed (e.g., failed to reach the cecum) - You have inflammatory bowel disease - You are being screened after previous treatment for colorectal cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREStandard colonoscopy

Colonoscopy standard (without CADe)

PROCEDUREColonoscopy CADe

colonoscopy with CADe


Locations(13)

CH de la Côte Basque

Bayonne, France

CHU Brest la Cavale Blanche

Brest, France

Clinique Paris Bercy

Charenton-le-Pont, France

CHU de Limoges

Limoges, France

Institut Paoli Calmettes

Marseille, France

Clinique Jules Verne

Nantes, France

CHU Nîmes

Nîmes, France

APHP - Hôpital Saint Antoine

Paris, France

Aphp-Hegp

Paris, France

CHU Bordeaux - Hôpital Haut Lévêque

Pessac, France

CHU de Rennes

Rennes, France

Clinique Pasteur

Toulouse, France

CHRU de Nancy - Hôpital Brabois Adultes

Vandœuvre-lès-Nancy, France

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NCT07299071


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