RecruitingNot ApplicableNCT07300696

Functional MRI for Monitoring Progression and Assessing Trends in ILD

Functional Magnetic Resonance Imaging of the Lung to Detect Regional Reversibility and Progression in Interstitial Lung Disease

Sponsor

University Hospital Heidelberg

Enrollment

200 participants

Start Date

Nov 20, 2025

Study Type

INTERVENTIONAL

Conditions

Interstitial Lung Diseases (ILD)

Summary

The main objective of this study is to investigate the utility of functional MRI to differentiate, characterize, and monitor subgroups of ILD. This can be broken down into three specific objectives: Determine if ILD features observed on high-resolution computed tomography (HRCT), such as ground glass opacities (GGO), are functionally different. Analyse MRI metrics within each subgroup to determine whether these metrics distinguish different ILDs. Assess MRI metrics longitudinally to see if these parameters change with disease progression, stability, or reversibility.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Lung MRI Protocol with Functional and Contrast-Enhanced Sequences for people with interstitial lung diseases (ild). The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTLung MRI Protocol with Functional and Contrast-Enhanced Sequences

Participants will undergo a lung MRI protocol consisting of structural imaging, non-contrast functional imaging, and contrast-enhanced imaging. Some sequences are custom-developed and performed during free breathing to accommodate patients with respiratory limitations.