RecruitingNot ApplicableNCT07302113

Complete Cognitive Intervention for cSLE

Promoting Health-Related Quality of Life in Pediatric Lupus Patients: Development and Implementation of a Tailored Brain Health Intervention


Sponsor

Andrea Knight

Enrollment

60 participants

Start Date

Jan 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This project will work closely with patients to design and test a new program that supports brain health in children and youth with childhood-onset lupus (cSLE). The investigators will see how practical and helpful the program is for patients.


Eligibility

Min Age: 13 YearsMax Age: 18 Years

Inclusion Criteria3

  • Receive subject-informed consent;
  • Have a current diagnosis of cSLE that meets the 1997 American College of Rheumatology (ACR) or System Lupus International Collaborating Clinics (SLICC) classification criteria
  • Aged 13-18 years old

Exclusion Criteria3

  • Conditions that significantly affect cognition (e.g., intellectual disability diagnosis, active psychosis), hearing loss or vision problems precluding participation in group
  • Non-English speaking
  • Lack of access to technology that would allow them to participate in the virtual intervention (e.g., phone, tablet, computer, etc.)

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Interventions

BEHAVIORALLupus Teen Online Problem Solving program

The Lupus Teen Online Problem Solving program is a brain health intervention developed to meet the needs of youth with childhood-onset lupus. The original Teen Online Problem Solving Program (TOPS) was developed for use with families impacted by traumatic brain injury. The Lupus Teen Online Problem Solving program is based on TOPS, with modifications to maximize relevance and accessibility. The intervention is a 10 session, evidence-based telehealth program providing training in problem-solving, emotion regulation, and communication skills in a one-to-one therapist-mediated design.


Locations(1)

The Hospital for Sick Children

Toronto, Ontario, Canada

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NCT07302113


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