RecruitingNCT07306468

Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life

Investigation of Exercise Capacity, Pulmonary Function, Respiratory Muscle Strength, and Quality of Life in Patients Diagnosed With Schizophrenia and Bipolar Disorder


Sponsor

Çankırı Karatekin University

Enrollment

150 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study aims to evaluate exercise capacity, pulmonary function, respiratory muscle strength, and quality of life in individuals diagnosed with schizophrenia and bipolar disorder. These psychiatric conditions are associated with sedentary lifestyles, metabolic side effects of psychotropic medications, and increased comorbidity risks, all of which may negatively impact physical fitness and respiratory health. By assessing cardiorespiratory endurance, pulmonary parameters (FVC, FEV₁), and respiratory muscle strength in this population, the study seeks to identify physiological limitations and contribute to the development of more effective rehabilitation strategies. The findings may support multidisciplinary approaches to improving physical health and overall quality of life in individuals with severe mental illness.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study measures how schizophrenia and bipolar disorder affect a person's ability to exercise, their lung function, and their quality of life, by comparing these measurements in people with these diagnoses against healthy volunteers. Understanding these differences may help improve the physical health care and exercise recommendations offered to people living with serious mental illness. **You may be eligible if...** - You are between 18 and 65 years old - You have a diagnosis of schizophrenia or bipolar disorder — or you are a healthy volunteer for comparison - You are willing to participate voluntarily **You may NOT be eligible if...** - You have a respiratory, cardiac, neurological, or orthopedic condition that could affect your breathing or exercise capacity - You have a neuropsychiatric condition other than schizophrenia or bipolar disorder Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERPulmonary Function Test

Participants' respiratory functions will assess with pulmonary function test according to ATS/ERS criteria

OTHERRespiratory Muscle Strength Evaluation

Participants' respiratory muscle strenght will assess with maximal inspiratory pressure and maximal expiratory pressure assessment according to ATS/ERS criteria

OTHERQuality of Life Assessment

Participants' quality of life will assess with WHOQOL-Bref questionnaire

OTHERExercise Capacity Assessment

Participants' exercise capacity will assess with 6 Minute Walk Test according to ATS/ERS criteria


Locations(1)

Çankırı Karatekin University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation

Çankırı, Çankırı, Turkey (Türkiye)

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NCT07306468


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