Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life
Investigation of Exercise Capacity, Pulmonary Function, Respiratory Muscle Strength, and Quality of Life in Patients Diagnosed With Schizophrenia and Bipolar Disorder
Çankırı Karatekin University
150 participants
Nov 1, 2025
OBSERVATIONAL
Conditions
Summary
This observational study aims to evaluate exercise capacity, pulmonary function, respiratory muscle strength, and quality of life in individuals diagnosed with schizophrenia and bipolar disorder. These psychiatric conditions are associated with sedentary lifestyles, metabolic side effects of psychotropic medications, and increased comorbidity risks, all of which may negatively impact physical fitness and respiratory health. By assessing cardiorespiratory endurance, pulmonary parameters (FVC, FEV₁), and respiratory muscle strength in this population, the study seeks to identify physiological limitations and contribute to the development of more effective rehabilitation strategies. The findings may support multidisciplinary approaches to improving physical health and overall quality of life in individuals with severe mental illness.
Eligibility
Inclusion Criteria2
- Being volunteer for participation
- Being 18 to 65 age
Exclusion Criteria2
- Having any respiratory, cardiac, neurologic or orthopedic disease which may affect respiratory functions or exercise capacity
- Having any neuropsychiatric disease except schizophrenia or bipolar disorder
Interventions
Participants' respiratory functions will assess with pulmonary function test according to ATS/ERS criteria
Participants' respiratory muscle strenght will assess with maximal inspiratory pressure and maximal expiratory pressure assessment according to ATS/ERS criteria
Participants' quality of life will assess with WHOQOL-Bref questionnaire
Participants' exercise capacity will assess with 6 Minute Walk Test according to ATS/ERS criteria
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07306468