Cognitive and Fusion Prostatic Biopsy
Cognitive Versus Image Guided Fusion Transrectal Prostatic Biopsy for the Detection of Prostate Cancer
Menoufia University
80 participants
Dec 28, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this study is to compare two different prostate biopsy techniques used to detect prostate cancer. These techniques are cognitive-targeted biopsy (CTB) and magnetic resonance imaging-ultrasound fusion-targeted transrectal biopsy (FTB). Both methods aim to improve the accuracy of prostate cancer detection by targeting suspicious areas identified on prostate imaging. This study will compare how accurately each technique detects prostate cancer, the pathological findings obtained from each biopsy method, and how operator performance may influence the procedure. The information gained from this study may help improve prostate cancer diagnosis and guide future biopsy practices.
Eligibility
Inclusion Criteria3
- Biopsy-naïve patients
- Prostate-specific antigen level between 4 and 20 ng/mL
- Multiparametric Magnetic Resonance Imaging Prostate Imaging-Reporting and Data System score 4 or 5
Exclusion Criteria3
- Prior prostate biopsy
- Prostate-specific Antigen level outside the specified range
- Contraindication to Magnetic Resonance Imaging
Interventions
Participants will undergo a cognitive-targeted prostate biopsy followed immediately by a fusion-targeted prostate biopsy during the same session.
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07306741