RecruitingNot ApplicableNCT07306741

Cognitive and Fusion Prostatic Biopsy

Cognitive Versus Image Guided Fusion Transrectal Prostatic Biopsy for the Detection of Prostate Cancer


Sponsor

Menoufia University

Enrollment

80 participants

Start Date

Dec 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to compare two different prostate biopsy techniques used to detect prostate cancer. These techniques are cognitive-targeted biopsy (CTB) and magnetic resonance imaging-ultrasound fusion-targeted transrectal biopsy (FTB). Both methods aim to improve the accuracy of prostate cancer detection by targeting suspicious areas identified on prostate imaging. This study will compare how accurately each technique detects prostate cancer, the pathological findings obtained from each biopsy method, and how operator performance may influence the procedure. The information gained from this study may help improve prostate cancer diagnosis and guide future biopsy practices.


Eligibility

Sex: MALE

Inclusion Criteria3

  • Biopsy-naïve patients
  • Prostate-specific antigen level between 4 and 20 ng/mL
  • Multiparametric Magnetic Resonance Imaging Prostate Imaging-Reporting and Data System score 4 or 5

Exclusion Criteria3

  • Prior prostate biopsy
  • Prostate-specific Antigen level outside the specified range
  • Contraindication to Magnetic Resonance Imaging

Interventions

PROCEDURECognitive-targeted prostate biopsy

Participants will undergo a cognitive-targeted prostate biopsy followed immediately by a fusion-targeted prostate biopsy during the same session.


Locations(2)

Menoufia university hospital urology department

Shibīn al Kawm, Egypt

Menoufia university hospital urology department

Shibīn al Kawm, Egypt

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NCT07306741


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