Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin
Does Computer-assist Virtual Lesion Segmentation Ushers to a Change in the Literature Consensus Regarding Mandibular Ameloblastoma Radiographic Safety Margin?. A Clinical Case Series
Alexandria University
10 participants
Jan 1, 2025
INTERVENTIONAL
Conditions
Summary
Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.
Eligibility
Inclusion Criteria2
- Patients with histologically confirmed ameloblastoma using a preoperative biopsy.
- Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.
Exclusion Criteria3
- Patients with lateral segmental mandibular defect involving the condyle.
- Patients with an active infection at the site of resection.
- Patients with recurrent lesion after resection.
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Interventions
Patient with mandibular ameloblastoma managed with virtual surgical planning \& Virtual lesion segmentation for the determination of a radiographic 10-mm safety margin.
Locations(1)
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NCT07306962