RecruitingNCT07307365

Evaluation of the Clinical Performance of the PremaSure Kit to Assess Premature Delivery Risk in Symptomatic Pregnant Patients


Sponsor

Rea Diagnostics SA

Enrollment

800 participants

Start Date

Dec 5, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of the study is to determine the clinical performance of the PremaSure kit, more precisely to assess whether the PremaSure kit can be used as a self-test to assess the risk of premature delivery in patients showing symptoms of premature delivery. The sensitivity and specificity of the test will be determined using as an outcome the delivery of the patient in the 7/14 days following the test. The simplified procedure is the following: 1. Patients are recruited and screened for eligibility criteria 2. A healthcare professional collects a vaginal swab from the patient 3. The collected sample is tested on the PremaSure kit 4. Pregnancy outcome is compared to the PremaSure kit's result


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria4

  • Informed Consent signed by the subject
  • Female patients above 18 years
  • Gestational week from 22w+0 days to 35w+6 days
  • Symptoms of prematurity.

Exclusion Criteria5

  • Subject lacking capacity to provide informed consent
  • Enrolment of the project leader, their family members, employees and other dependent persons
  • Patients with ruptured amniotic membranes or blood in their vaginal discharge
  • Patients with vaginal examination in the last 24 hours
  • Previous enrolment in the current study

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Locations(1)

Centre Hospitalier Universtaire Vaudois (CHUV)

Lausanne, Canton of Vaud, Switzerland

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NCT07307365


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