Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

This study tests a new catheter-based heart procedure using the Sphere-360 catheter and Affera mapping system to treat paroxysmal atrial fibrillation (PAF) — a type of irregular heartbeat that comes and goes — by creating precise ablation (scar tissue) in the heart to block the abnormal electrical signals. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with recurrent symptomatic paroxysmal atrial fibrillation (PAF), with at least 2 symptomatic episodes in the past 6 months and at least one confirmed on an ECG in the past 12 months - Each AF episode lasts more than 30 seconds but stops on its own or with treatment within 7 days - You are willing and able to complete all follow-up visits **You may NOT be eligible if...** - You have persistent or permanent atrial fibrillation (where it does not stop on its own) - You have had previous ablation for AF - You have other significant heart conditions or structural heart disease Talk to your doctor to see if this trial is right for you.