Limited Versus Extended Lymph Node Dissection During Radical Prostatectomy in Patients With Localized or Locally Advanced Prostate Cancer

This study compares two surgical approaches for removing lymph nodes during prostate removal surgery (radical prostatectomy) — a limited dissection versus a more extensive extended dissection — to determine which approach leads to better cancer outcomes while minimizing side effects. **You may be eligible if...** - You are over 18 years old - You have a confirmed diagnosis of localized or locally advanced prostate cancer (adenocarcinoma) - There is no evidence that cancer has spread to distant parts of the body (no metastases) - Your tumor can be surgically removed based on imaging and physical exam - Your general health and life expectancy make you a suitable candidate for radical prostatectomy **You may NOT be eligible if...** - You have another active invasive cancer - You have a contraindication to pelvic lymph node dissection - You have already received treatments that conflict with the study Talk to your doctor to see if this trial is right for you.