RecruitingPhase 2NCT07309276

A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer


Sponsor

Shanghai Junshi Bioscience Co., Ltd.

Enrollment

864 participants

Start Date

Jan 23, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a multicenter, open-label Phase II clinical study, with the main objective being to evaluate the investigator-assessed objective response rate of JS212 in combination therapy for advanced lung cancer. The aim is to explore the safety, tolerability, and preliminary efficacy of JS212 combined with JS207, Toripalimab, JS213 combined or not combined with chemotherapy.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called JS207 for Injection, a drug called JS212 for Injection, and others for people with advanced lung cancer. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGJS212 for Injection

Administered by intravenous infusion on Day 1 of each 21-day cycle.

DRUGJS207 for Injection

Administered by intravenous infusion on Day 1 of each 21-day cycle.

DRUGToripalimab

Administered by intravenous infusion on Day 1 of each 21-day cycle.

DRUGJS213 for Injection

Administered by intravenous infusion on Day 1 of each 21-day cycle.


Locations(1)

Shanghai East Hospital

Shanghai, Shanghai Municipality, China

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NCT07309276


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