RecruitingNCT07310446

Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance

Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance (PROVE)

Sponsor

Universal Diagnostics

Enrollment

6,500 participants

Start Date

Jul 31, 2023

Study Type

OBSERVATIONAL

Conditions

Colorectal, Cancer

Summary

This study is designed to prospectively collect blood samples and clinical data from patients that have been newly diagnosed with colorectal cancer and scheduled for resection surgery but are pre cancer treatment, subjects who are NOT scheduled for surgery but have histological confirmation of CRC from the diagnostic colonoscopy and clinical staging (cTMN) is available and are pr e- treatment, and patients who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy examinations.

Eligibility

Min Age: 45 YearsMax Age: 84 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting blood samples from people in the United States to help improve and test a blood test that detects colorectal cancer (bowel cancer) using fragments of cancer DNA floating in the bloodstream. Two groups are included: people already diagnosed with colorectal cancer, and people getting a routine colonoscopy screening. **You may be eligible if...** - You have been diagnosed with colorectal cancer (and are not currently undergoing treatment), OR - You are scheduled for a colonoscopy as routine colorectal cancer screening and have no prior history of colorectal cancer **You may NOT be eligible if...** - You are currently receiving treatment for colorectal cancer - You have had colorectal cancer in the past (if you're in the screening group) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Gastroenterology and Internal Medicine Specialists

Lake Barrington, Illinois, United States

View Full Details on ClinicalTrials.gov

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NCT07310446

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