Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
A Randomized Controlled Trial Comparing Mirabegron and Tamsulosin for Ureteral Stone Expulsion and Clinical Symptom Improvement
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
500 participants
Feb 13, 2026
INTERVENTIONAL
Conditions
Summary
This randomized controlled trial compares the efficacy and safety of four treatment strategies for ureteral stone expulsion: Mirabegron alone, Tamsulosin alone, a combination of both, and standard conservative care. Participants diagnosed with ureteral stones will be randomly assigned to one of these four groups. The primary objective is to evaluate the stone expulsion rate within 4 weeks. The study also assesses time to expulsion, pain intensity, analgesic use, and potential side effects.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
50 mg tablet orally once daily.
0.4 mg tablet orally once daily.
Locations(1)
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NCT07310797