RecruitingPhase 2NCT07314060

A Clinical Trial of TQH2929 Injection in Patients With Acute Flare-up of Generalized Pustular Psoriasis

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Clinical Trial Evaluating the Efficacy and Safety of TQH2929 Injection in Patients With Acute Exacerbations of Generalized Pustular Psoriasis

Sponsor

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Enrollment

36 participants

Start Date

Mar 19, 2026

Study Type

INTERVENTIONAL

Conditions

Generalized Pustular Psoriasis

Summary

This is a multicenter, randomized, double-blind, placebo-controlled phase II clinical study, all subjects need to use TQH2929 injection/placebo. The aim was to demonstrate the efficacy and safety of TQH2929 injection in patients with acute exacerbations of generalized pustular psoriasis, with a total of 36 subjects.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called TQH2929 Injections and a drug called TQH2929 Placebo for people with generalized pustular psoriasis. The study is currently recruiting participants at 32 locations. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTQH2929 Injections

TQH2929 is a humanized monoclonal antibody that interfering with the signal cascade.

DRUGTQH2929 Placebo

Placebo contains no active substance.

Locations(32)

Peking University First Hospita

Beijing, Beijing Municipality, China

Peking University Third Hospital

Beijing, Beijing Municipality, China

The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

Southern Medical University Dermatology Hospital

Guangzhou, Guangdong, China

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

The Affiliated Hospital of Guizhou Medical University

Guiyang, Guizhou, China

The Second Hospital Of Hebei Medical University

Shijiazhuang, Hebei, China

The Second Affiliated Hospital of Henan University of science and technology

Luoyang, Henan, China

Zhengzhou Central Hospital

Zhengzhou, Henan, China

Henan Provincial People's Hospital

Zhengzhou, Henan, China

The fifth Affiliated hospital of zhengzhou university

Zhengzhou, Henan, China

Shiyan Renmin Hospital

Shiyan, Hubei, China

Renmin Hospital of Wuhan University

Wuhan, Hubei, China

The First Hospital of Hunan University of Chinese Medicine

Changsha, Hunan, China

Xiangya Hospital of Central South University

Changsha, Hunan, China

The General Hospital Of Hunan University Of Medicine

Huaihua, Hunan, China

The first hospital of jilin university

Changchun, Jilin, China

The first hospital of china medical university

Shenyang, Liaoning, China

Shandong First Medical University Affiliated Dermatology Hospital

Jinan, Shandong, China

Shanghai Skin Disease Hospital

Shanghai, Shanghai Municipality, China

The Second Affiliated Hospital of Xi'an Jiaotong University

Xi’an, Shanxi, China

Chengdu Second People's Hospital

Chengdu, Sichuan, China

Sichuan Provincial People' s Hospital

Chengdu, Sichuan, China

The Affiliated Hospital of Southwest Medical University

Luzhou, Sichuan, China

The Affiliated Hospital of Southwest Medical University

Luzhou, Sichuan, China

Tianjin Medical University General Hospital

Tianjin, Tianjin Municipality, China

Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

Tianjin, Tianjin Municipality, China

People's Hospital of Xinjiang Uygur Autonomous Region

Ürümqi, Xinjiang, China

The First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China

The First Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, China

Jiaxing First Hospital

Jiaxing, Zhejiang, China

The first affiliated hospital of ningbo university

Ningbo, Zhejiang, China

View Full Details on ClinicalTrials.gov

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