Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever
"Comparing Efficacy of Intravenous Azithromycin and Meropenem for Extensively Drug-Resistant Enteric Fever: A Randomized Controlled Trial" (Pilot Study)
Indus Hospital and Health Network
40 participants
Apr 22, 2025
INTERVENTIONAL
Conditions
Summary
1. Primary Objective: o To evaluate the efficacy of intravenous azithromycin compared with meropenem in the treatment of extensively drug-resistant (XDR) enteric fever. 2. Secondary Objectives: * To evaluate the fever defervescence and Salmonella Typhi eradication * To evaluate the cost-effectiveness of intravenous azithromycin versus meropenem in treating XDR enteric fever. 3. Exploratory Objectives: * To evaluate the drug resistance against intravenous azithromycin versus in treating XDR enteric fever.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Azithromycin 1g IV loading dose then 500mg IV OD
Meropenem 1000 mg IV Q8H
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07314281