RecruitingNCT07314580

Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients

Clinical, Radiographic, Functional and Psychosocial Evaluation of Premolar Autotransplantation to the Anterior Maxillary Region in Young Patients: An Ambispective Observational Study

Sponsor

University of Barcelona

Enrollment

50 participants

Start Date

Dec 1, 2019

Study Type

OBSERVATIONAL

Conditions

Tooth-loss Tooth Injury

Summary

This study aims to evaluate the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients. The study has an ambispective observational design, including a retrospective cohort (patients treated between December 2019 and December 2025) and a prospective cohort (patients enrolled until December 2028). Participants aged 7 to 15 years who received or will receive premolar autotransplantation to replace an anterior tooth will be followed clinically and radiographically for up to 5 years. Outcomes include tooth survival, periodontal and pulpal healing, root development, complications, orthodontic interactions, restorative needs, and patient satisfaction. The study seeks to identify prognostic factors and long-term success indicators for dental autotransplantation in growing patients.

Eligibility

Min Age: 7 YearsMax Age: 15 Years

Inclusion Criteria6

Patients aged 7 to 15 years.
ASA I classification.
Loss or indication for extraction of a maxillary anterior tooth (teeth 12, 11, 21, or 22) due to trauma, resorption, or restorative reasons.
Availability of a donor first or second premolar with root development between one-half and complete root length.
Ability to complete at least 2 years of follow-up.
Parent/guardian consent and minor assent obtained for prospective cases.

Exclusion Criteria4

Patients older than 15 years.
Severe systemic disease.
Inability or unwillingness to attend scheduled follow-up visits.
Lack of a suitable donor premolar.

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Interventions

PROCEDUREPremolar Autotransplantation

Premolar autotransplantation performed using a standardized clinical protocol including digital planning (CBCT and STL models), 3D-printed donor tooth replicas, guided or conventional socket preparation, atraumatic donor extraction, extraoral time under 5 minutes and semirigid splinting. Clinical and radiographic follow-up is performed up to 5 years.