RecruitingPhase 3NCT07314905

Adaptive Platform Trial of Treatments for Respiratory Infections in Community Settings (TreatResp)

Adaptive Platform Trial of Treatments for Respiratory Infections in Community Settings


Sponsor

Unity Health Toronto

Enrollment

264 participants

Start Date

Apr 29, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

TreatResp is a double-blind, individually randomized, multi-centre adaptive platform trial. TreatResp aims to establish an adaptive platform trial aimed at evaluating the clinical- and cost-effectiveness, practical challenges, and outcomes of therapeutics for respiratory pathogens in non-hospitalized patients. Participants will be randomized to receive usual care (i.e., supportive care and symptom relief) or a study therapeutic, which will be determined by the TreatResp Therapeutics Committee. The primary outcomes being evaluated is time to recovery.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Baloxavir and a drug called Placebo Control for people with acute respiratory infections (aris), influenza a, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGBaloxavir

This is a sub-protocol within the TreatResp adaptive platform trial to compare the clinical and cost-effectiveness of Baloxavir, a single 40mg or 80 mg tablet based on patient weight, to a matching placebo among non-hospitalized patients with mild to moderate influenza A/B. This sub-protocol is part of the influenza domain within TreatResp.

DRUGPlacebo Control

Matching placebo for Baloxavir


Locations(1)

Unity Health Toronto

Toronto, Ontario, Canada

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NCT07314905


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