Phase II Clinical Study of HRS-9057 Injection in Patients With Heart Failure-induced Fluid Retention

This study is testing a new drug called HRS-9057 in people with heart failure who are retaining excess fluid (edema) and whose condition is not responding well to standard water pills (diuretics). **You may be eligible if...** - You are 18 or older - You have been hospitalized for acute heart failure within the past 24 hours - You have symptoms of heart failure (e.g., shortness of breath at rest, swollen legs, fluid in the lungs) and elevated BNP levels in your blood - Standard diuretic medication has not adequately reduced your fluid buildup **You may NOT be eligible if...** - You had a heart attack, stroke, or serious heart rhythm problem in the past month - You had major surgery or a serious infection in the past month - You recently had coronary stenting, bypass surgery, ablation for heart rhythm problems, or a pacemaker implanted - You have severe kidney failure or other major organ problems Talk to your doctor to see if this trial is right for you.