Evaluation of Emotion-related Salivary Molecular Biomarkers
Evaluation of Emotion-related Salivary Molecular Biomarkers Following Olfactory Stimuli
Sys2Diag
240 participants
Nov 14, 2022
OBSERVATIONAL
Conditions
Summary
Recent studies show that emotional states can be discriminated by physiological responses. This physiological regulation results from the action of enzymes and hormones that represent the activity of the autonomic nervous system. The measurement of specific biomarkers, using non-invasive biological tests in saliva, would therefore provide physiological data on an individual's emotional state in response to stimuli, particularly olfactory stimuli.
Eligibility
Inclusion Criteria7
- Subject willing to follow study procedures
- Subject able to understand the purpose, nature and methodology of the study
- Subject has signed informed consent form
- Subjects between 18 and 60 years of age.
- Pregnant or breastfeeding women
- Subjects presenting anosmia during the last 15 days
- Subjects presenting symptoms and signs of active oral inflammation, advanced periodontitis or severe gingivitis.
Exclusion Criteria3
- Subjects deprived of liberty, protected adults, vulnerable persons or minors
- Subjects with a proven or suspected chronic infectious disease that could entail a risk of contamination during sample handling (laboratories not equipped to handle this type of sample)
- Rejection to sign the consent form.
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Interventions
Levels of the biomarkers of interest (DHEA, pg/mL; Oxytocin, pg/mL; Cortisol, pg/mL; Alpha Amylase, U/mL) will be measured in the saliva of participating subjects by enzymatic assay methods or ELISA-type methods performed using commercial kits.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07320040