Patient-specific Reconstruction Plate for Segmental Mandibular Defects
Patient-specific Reconstruction Plate for Alloplastic Bridging of Segmental Mandibular Defects. A Clinical and Radiographic Study.
Alexandria University
14 participants
Jan 1, 2025
INTERVENTIONAL
Conditions
Summary
The mandible's horseshoe-shaped anatomy makes the reconstruction of segmental defects a challenging procedure. Conventional reconstruction typically relies on alloplastic plates to bridge bony stumps; however, these require extensive intraoperative bending, often resulting in imperfect adaptation, press-to-contact fixation, and residual stresses that increase the risk of hardware fatigue and fracture. Recent advances in computer-aided design and manufacturing (CAD/CAM) and virtual surgical planning (VSP) have improved precision in maxillofacial reconstruction. Patient-Specific Reconstruction Plates (PSRP), developed from virtual planning and patient-specific anatomical data, offer a bespoke contour adaptation, predictable screw positioning, and elimination of press-fit deformation. This customization improves alignment, mechanical stability, and long-term outcomes.
Eligibility
Inclusion Criteria7
- Patients with a segmental mandibular continuity defect, not involving the condyle.
- Patients suffering from benign, locally invasive or malignant lesions that involving the lower border of the mandible.
- Patients with recurrent lesions after resection.
- Patients dealing with osteomyelitis or jaw osteonecrosis that is indicated for sequestrectomy.
- • Stage-III jaw osteonecrosis.
- Patients with traumatic defects.
- Patients with post-gunshot mandibular defects.
Exclusion Criteria4
- Medically compromised patients contradict the operation.
- Patients with segmental mandibular defects that require condylar process resection
- Patients with lateral segmental mandibular defects involving the condyle that require reconstruction using an alloplastic total joint.
- Patients with an active infection at the site of resection.
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Interventions
Patient specific reconstruction plate
Locations(1)
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NCT07320924