The Optimal Measurement Time for the New Gallbladder Function Assessment Method
The Optimal Measurement Time for the New Gallbladder Function Assessment Method: A Prospective, Multicenter, Double-Blind, Crossover Trial
Hepatopancreatobiliary Surgery Institute of Gansu Province
120 participants
Jan 7, 2026
INTERVENTIONAL
Conditions
Summary
This is a multicenter, prospective, randomized, double-blind, crossover study involving healthy individuals, aiming to evaluate the stability of oral protein bars + olive oil as a new method for determining gallbladder contraction function and its optimal diagnostic time window.
Eligibility
Inclusion Criteria1
- Ultrasound assessment identifies people with normal biliary tract structure.
Exclusion Criteria22
- History of Endoscopic Retrograde Cholangiopancreatography
- Previous gallstone removal surgery with gallbladder preservation
- Other biliary tract diseases and related surgical history
- History of acute or chronic pancreatitis
- History of gastrointestinal surgery
- Gastrointestinal obstruction
- Dysfunction of the sphincter of Oddi
- Gallbladder neck polyps
- Abnormal gallbladder structure
- Gallbladder mass
- Biliary infection or stones
- Congenital biliary abnormalities
- Biliary injury or surgery
- Biliary tumors
- Gastrointestinal bleeding, liver cirrhosis, or other malignant diseases
- Significant arrhythmia, bradycardia, or atrioventricular block
- Severe hypertension, liver or kidney insufficiency
- Immune, endocrine, hematological, or mental disorders
- Severe cerebrovascular disease
- Allergy to relevant foods
- Pregnant or breastfeeding women
- Unwillingness or inability to consent to participation
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Interventions
First, the intervention of oral administration of 2 fried eggs is carried out. The size of the gallbladder is evaluated by ultrasound examination. The washout period is 1 week. After that, the first intervention process of group B is repeated.
First, an intervention with oral protein bars + 50ml olive oil is conducted. The size of the gallbladder is evaluated through ultrasound examination. The washout period is 1 week. After that, the first intervention process of Group A is repeated.
Locations(5)
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NCT07321431