RecruitingNot ApplicableNCT07323368

Advancing Reperfusion Therapy for Ischemic Stroke: Perfusion-guided Endovascular Intervention for Medium Vessel Occlusion Therapy

Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Perfusion-guided Endovascular Intervention for Medium Vessel Occlusion Therapy (PIVOT)


Sponsor

Beijing Tiantan Hospital

Enrollment

568 participants

Start Date

Feb 8, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators initiated a multicenter, prospective, randomized, open label, blinded-endpoint (PROBE) controlled trial to evaluate the efficacy and safety of perfusion-guided endovascular treatment (EVT) compared to standard medical care for patients with acute ischemic stroke due to medium vessel occlusion (MeVO) within 24 hours from symptom onset.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Best medical treatment (BMT) and a procedure called Endovascular treatment for people with medium vessel occlusions and stroke, ischemic. The study is currently recruiting participants at 6 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREEndovascular treatment

EVT included thrombectomy with stent retrievers, thromboaspiration, intraarterial thrombolysis, balloon angioplasty, stenting, or a combination of these approaches at the discretion of the interventional team.

DRUGBest medical treatment (BMT)

Administration of BMT should be done according to routine clinical practice and current international guidelines. Administration of BMT must not be delayed by randomisation and should be done independently from participation in this trial.


Locations(6)

Beijing tiantan hospital

Beijing, Beijing Municipality, China

Beijing Daxing District People's Hospital

Beijing, Beijing Municipality, China

Xingtang County People's Hospital

Longzhou, Hebei, China

Luoyang Yiluo Hospital

Luoyang, Henan, China

People's Hospital of Queshan

Panlong, Henan, China

Changle People's Hospital

Changle, Shandong, China

View Full Details on ClinicalTrials.gov

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NCT07323368


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