RecruitingNot ApplicableNCT07324070
Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression
New Methods Electroconvulsive Therapy Augmentation
Sponsor
Charles University, Czech Republic
Enrollment
50 participants
Start Date
Jan 5, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
The RTMSECT2 study was design to compare the application of electroconvulsive therapy augmented by transcranial magnetic stimulation. Subject will be compared both within groups and in group using psychometric scales and different deliver energy
Eligibility
Min Age: 18 Years
Inclusion Criteria3
- Age equal to 18 or higher
- MADRS (Montgomery-Asberg Depression Scale) qual or higher than 20
- Major depressive disorder according to ICD 10
Exclusion Criteria9
- Other axis 1 disorder (for example schizofrenia, addiction, etc.)
- No dementia
- ECT in the last 3 months
- TMS in the last 3 months
- Psychotic disease or symptoms
- Ppregnancy or lactation
- Any neurological disease (for example epilepsy, etc.)
- Participation in another clinical trial within the last 30 days
- somatic condition which contraindicates ECT
Interventions
DEVICEElectroconvulsive therapy
transcranial magnetic stimulation in intermitent theta burst stimulation protocol plus electroconvulsive therapy
DEVICETranscranial Magnetic Stimulation
Transcranial magnetic stimulation, intermitent theta burst stimulation or sham TMS
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07324070
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