RecruitingNCT07324551

Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center


Sponsor

Ohio State University

Enrollment

100 participants

Start Date

Nov 3, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to evaluate the function of matched pair Aristotle 14 Guidewire and Plato Microcatheter in MMA embolization treatment for chronic subdural hematoma compared to surgeon's preference


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age ≥ 18 years old
  • Patient or legally authorized representative (LAR) signs an informed consent form
  • Confirmed diagnosis of subacute or chronic subdural hematoma, defined as 50% or more chronic blood
  • Pre-morbid Modified Rankin Score of ≤ 3

Exclusion Criteria6

  • Age \< 18 years old
  • Potentially dangerous anatomic variations leading to increased procedural risk or unsafe access for MMA embolization
  • Unmanaged, uncontrolled bleeding disorders/blood diathesis
  • Presumed septic embolus, or suspicion of microbial superinfection
  • Contraindication to angiography
  • CT or MRI evidence of intra-cranial tumor or mass lesion

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Interventions

DEVICEMatched pair Aristotle 14 guidewire and Plato 17 microcatheter

Participants will be randomized in 1:1 ratio to either use of study devices (matched pair Aristotle and Plato) or standard of care (surgeon combination preference) using block randomization method with a fixed block size of 4 ensuring 50% will be randomized to study devices group and 50% randomized to standard of care group.

DEVICESurgeon combination preference

Surgeon will decide the on guidewire and microcatheter to use for MMA embolization


Locations(1)

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States

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NCT07324551


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