Ultrasound Guided External Oblique and Rectus Abdominis Plane Block (EXORA) on Neuroendocrine Stress Response in Adults Undergoing Umbilical Hernia Surgery
The Effect of Ultrasound Guided External Oblique and Rectus Abdominis Plane Block (EXORA) on Neuroendocrine Stress Response in Adults Undergoing Umbilical Hernia Surgery: A Prospective Randomized Controlled Trial
Tanta University
100 participants
Aug 1, 2025
INTERVENTIONAL
Conditions
Summary
This study aims to evaluate the efficacy of ultrasound-guided external oblique and rectus abdominis plane block on the neuroendocrine stress response and postoperative analgesia in adults undergoing umbilical hernia repair.
Eligibility
Inclusion Criteria4
- Aged from 21 to 65 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) Physical status I and Ⅱ.
- Schedule for elective umbilical hernia surgery under general anesthesia.
Exclusion Criteria9
- ASA Ⅲ or Ⅳ.
- Patients with metabolic abnormalities, e.g., diabetes mellitus.
- Patients receiving corticosteroids.
- History of allergies to local anesthetics.
- Bleeding or coagulation disorders.
- Anatomical abnormalities.
- Psychiatric and neurological disorders.
- Complicated hernial defect (obstructed).
- Patient refusal.
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Interventions
Patients will receive general anesthesia only.
Patients will receive general anesthesia and an external oblique and rectus abdominis plane (EXORA) block with 0.25% bupivacaine.
Locations(1)
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NCT07324863