RecruitingNCT07332117
A Pilot Study to Assess Body Mass Composition Measurement Using BIA and Muscle Ultrasound in IPF and PPF Patients on Anti-fibrotic Medications
Sponsor
Royal Brompton & Harefield NHS Foundation Trust
Enrollment
30 participants
Start Date
Sep 9, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
To assess the impact on body mass composition from anti-fibrotic medications used in fibrotic lung disease by using BIA and muscle ultrasound
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- A diagnosis of Idiopathic pulmonary fibrosis or progressive pulmonary fibrosis
- Newly commencing anti-fibrotic medication (either nintedanib or pirfenidone)
- Subject aged > 18 years
- Able to willingly give consent
Exclusion Criteria9
- Co-morbidities currently requiring enteral feeding
- Weight loss > 10% in preceding 3-6 months
- Significant musculoskeletal issues that may impact muscle mass
- End of life care (expected < 6 weeks left to live)
- Previous anti-fibrotic use
- Currently on > Prednisolone 10mg daily
- Presence of implantable cardioverter defibrillator (ICD) or permanent pacemaker (PPM)
- Heart failure
- Pregnancy
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Interventions
OTHERNo Interventions
No intervention
OTHERNo intervention
No intervention
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07332117
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