RecruitingNot ApplicableNCT07333040

HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids

Hemorrhoidectomy, Energy-Based, and Laser Outcomes in Grade III Hemorrhoids: A Prospective, Multicenter, Preference-Based Comparative Study


Sponsor

Chang Gung Memorial Hospital

Enrollment

60 participants

Start Date

Jul 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), and conventional closed hemorrhoidectomy (Ferguson technique). Due to strong patient preferences in hemorrhoidal surgery, this study utilizes a pragmatic, preference-tolerant design. Eligible patients will undergo standardized counseling and select their preferred treatment arm. The study aims to evaluate whether minimally invasive energy-based therapies offer superior postoperative pain relief and faster functional recovery compared to conventional hemorrhoidectomy


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Ferguson Hemorrhoidectomy, a procedure called Hemorrhoid Energy Therapy (HET), and others for people with hemorrhoids third degree, internal hemorrhoids, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURELaser Hemorrhoidoplasty (LHP)

1470nm or 980nm diode laser ablation

PROCEDUREHemorrhoid Energy Therapy (HET)

Bipolar radiofrequency coagulation using HET™ system

PROCEDUREFerguson Hemorrhoidectomy

Standard closed excisional hemorrhoidectomy


Locations(1)

Chang Gung Memorial Hospital, Linkou Branch

Taoyuan, Taiwan

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NCT07333040


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