Clinical Efficacy of Transarterial Infusion Chemotherapy for Unresectable Colorectal Cancer

This study is evaluating the effectiveness of delivering chemotherapy directly into the arteries supplying a colorectal tumor (transarterial infusion chemotherapy) for patients whose cancer cannot be removed by surgery. **You may be eligible if...** - You are 18 or older - You have been diagnosed with colorectal cancer confirmed by CT/MRI and biopsy - Surgery is not an option due to your health or the size/location of the tumor - You have not previously received chemotherapy, or your cancer still responds to chemotherapy - Your blood counts and organ function (liver, kidneys, heart) meet the required thresholds **You may NOT be eligible if...** - You have another primary cancer elsewhere in the body - You have a hole (perforation) in your gut - You are allergic to the chemotherapy drugs being used - You are pregnant, breastfeeding, or planning pregnancy - You are receiving other cancer treatments at the same time Talk to your doctor to see if this trial is right for you.