RecruitingNot ApplicableNCT07335224

Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture

MPOWER: A Pilot Trial Among Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture


Sponsor

Inova Health Care Services

Enrollment

24 participants

Start Date

Jan 8, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Prostate cancer is the most common cancer among men in the United States. Many men with prostate cancer are treated with hormone therapy, also called androgen deprivation therapy (ADT). While this treatment is effective, it often causes bothersome side effects such as hot flashes, poor sleep, fatigue, and other physical and emotional symptoms. There is currently no standard treatment to help manage these side effects in men. Acupuncture is a non-drug treatment that has been shown to help reduce hot flashes and related symptoms in women receiving hormone therapy for breast cancer. However, much less is known about whether acupuncture is helpful for men receiving hormone therapy for prostate cancer. This study will test whether an acupuncture program, combined with usual lifestyle education, is feasible and acceptable for men undergoing ADT. The study will also explore whether acupuncture may help reduce hot flashes and improve related symptoms. A total of 24 men with prostate cancer receiving ADT will be randomly assigned to one of two groups: one group will begin acupuncture right away, and the other group will begin acupuncture after a delay, with regular check-ins during the waiting period. All participants will receive standard lifestyle education. Participants will be followed for about five months and will be asked to complete daily hot flash diaries, questionnaires about their symptoms and quality of life, and wear a Fitbit to track sleep. The results of this pilot study will help determine whether a larger study should be conducted to better understand the role of acupuncture in managing hormone therapy side effects in men with prostate cancer.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether acupuncture can reduce the severity and daily impact of hot flashes in men with prostate cancer who are receiving androgen deprivation therapy (ADT) — a hormone treatment that commonly causes significant hot flashes. **You may be eligible if...** - You are male, 18 or older - You have been diagnosed with any stage of prostate cancer - You are currently receiving androgen deprivation therapy (ADT) and/or androgen receptor-blocking drugs - You experience moderate to severe hot flashes that interfere with your daily life (score of 4 or higher on a standard scale) - Your overall health is good (ECOG 0–1) **You may NOT be eligible if...** - You have a severe or uncontrolled medical condition or infection - You are allergic to acupuncture needles - You have used acupuncture for hot flashes within the past 6 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAcupuncture

Acupuncture is a form of alternative medicine and a component of traditional Chinese medicine (TCM) in which thin needles are inserted into the body

BEHAVIORALLifestyle Management

lifestyle education per usual care without acupuncture for the first 10 weeks. At week 12, they will begin the acupuncture protocol (weekly 30-minute sessions).


Locations(1)

Inova Schar Cancer Institute

Fairfax, Virginia, United States

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NCT07335224


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