ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty
Effect of ERAS-Based Preoperative Nutrition Education and Fasting Protocol on Postoperative Hydration Status and Nausea-Vomiting in Patients Undergoing Total Knee Arthroplasty
Nermin Ocaktan
72 participants
Dec 26, 2025
INTERVENTIONAL
Conditions
Summary
The aim of this randomized controlled study is to investigate the effect of implementing a preoperative nutrition education and fasting protocol prepared in accordance with Enhanced Recovery After Surgery (ERAS) guidelines during the 24-hour preoperative period on postoperative hydration status and the incidence of nausea and vomiting in patients scheduled for total knee arthroplasty. Total knee arthroplasty is a commonly performed surgical procedure, particularly in older adults, and postoperative recovery may be negatively affected by surgical stress, anesthesia-related complications, dehydration, and postoperative nausea and vomiting. ERAS protocols emphasize the optimization of preoperative nutrition and hydration as key components to improve postoperative outcomes. In this study, patients undergoing elective total knee arthroplasty will be randomly assigned to an intervention group or a control group. Patients in the intervention group will receive ERAS-based preoperative nutrition education and a standardized fasting protocol during the 24 hours prior to surgery, while patients in the control group will receive routine standard care. Postoperative hydration status, nausea and vomiting severity, and fluid intake-output balance will be assessed and compared between the two groups. The findings of this study are expected to contribute to improving perioperative nursing care practices and enhancing patient recovery and comfort following total knee arthroplasty.
Eligibility
Inclusion Criteria5
- Adults aged 18 years and older.
- Patients scheduled for elective total knee arthroplasty.
- Patients expected to be hospitalized for at least 48 hours postoperatively.
- Ability to communicate verbally and provide informed consent.
- Patients with adequate cognitive and neurological capacity to understand study procedures.
Exclusion Criteria5
- Presence of any chronic disease requiring fluid restriction.
- Diagnosed cognitive impairment or psychiatric disorders affecting comprehension (e.g., Alzheimer's disease, dementia, psychotic disorders).
- Acute conditions causing dehydration in the preoperative period (e.g., vomiting, diarrhea, excessive fluid loss).
- Intraoperative complications requiring intensive care unit admission.
- Postoperative follow-up shorter than 48 hours due to early discharge or transfer to another clinic.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
A structured preoperative nutrition education program and evidence-based fasting protocol developed in accordance with ERAS guidelines, implemented during the 24 hours prior to total knee arthroplasty.
Participants receive routine preoperative care according to standard institutional clinical practice without ERAS-based nutrition education or fasting protocol.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07336160