RecruitingNCT07338240

SOFA-2 Score in Turkish ICUs

Real-Time Validation and Feasibility of the SOFA-2 Score in Adult Intensive Care Units in Türkiye (TR-SOFA2): A Multicenter Prospective Observational Study


Sponsor

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital

Enrollment

5,200 participants

Start Date

Jan 19, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to evaluate how well a new scoring system called the Sequential Organ Failure Assessment-2 (SOFA-2) works in adult intensive care units in Türkiye. SOFA-2 is designed to measure the severity of organ dysfunction in critically ill patients using routinely collected clinical and laboratory data. It is an updated version of the original SOFA score and reflects modern intensive care practices. In this multicenter observational study, adult patients admitted to participating intensive care units will be followed during their ICU stay. SOFA and SOFA-2 scores will be calculated during the first 24 hours of admission, and in patients with longer stays, additional scores will be recorded. No additional tests or treatments will be performed as part of the study. The main goal of the study is to examine the relationship between SOFA-2 scores and intensive care unit mortality. The results are expected to help clinicians better assess disease severity and outcomes in critically ill patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adults aged 18 years or older
  • Admission to a participating intensive care unit in Türkiye
  • Intensive care unit stay longer than 24 hours

Exclusion Criteria4

  • Patients younger than 18 years
  • Pregnant patients
  • Organ donors
  • Patients with unknown intensive care unit discharge outcomes

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Locations(1)

University of Health Sciences Turkey, İzmir School of Medicine, Dr. Suat Seren Chest Disease and Thoracic Surgery Training and Research Hospital, Intensive Care Unit

Izmir, İzmir, Turkey (Türkiye)

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NCT07338240


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