RecruitingNCT07339800

Chest CT Scan in Pulmonary Mucormycosis: Prognostic Value


Sponsor

University Hospital, Strasbourg, France

Enrollment

80 participants

Start Date

Sep 18, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Invasive pulmonary fungal infections caused by Mucorales are rare but severe and rapidly progressive, affecting immunocompromised patients. The role of chest imaging in their diagnosis is well established in the 2020 EORTC/MSGERC criteria, and its use is almost systematic. However, the progression of lung parenchymal involvement and any potential prognostic radiological patterns in the follow-up of these infections are less well understood. This research aims to identify imaging characteristics predictive of favorable or unfavorable outcomes in infected patients, in order to better tailor follow-up and therapeutic options.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Patients aged 18 years or older
  • Treated at Strasbourg University Hospital between January 1, 2009, and June 3, 2025
  • With a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria
  • Having undergone at least one CT scan including the thoracic region

Exclusion Criteria2

  • No CT scan including the thoracic region
  • No diagnosis of probable or proven invasive pulmonary infection with Mucorales (EORTC/MSGERC 2020 criteria)

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Locations(1)

Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France

Strasbourg, France

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NCT07339800