Pistachio Snacking and Metabolic Flexibility
Effects of Pistachio Snacking on Metabolic Flexibility in Healthy Overweight and Obese Adults
University of South Carolina
60 participants
Sep 1, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Secondary goals include evaluating effects on changes in diet quality, sleep characteristics, physical activity, and hormonal health in women. In randomized order, participants will complete four days of pistachio snacking and four days of normal dietary habits (control). For both conditions, primary outcomes of resting substrate metabolism, metabolic flexibility during exercise, and post-exercise substrate metabolism will be measured pre-post intervention via indirect calorimetry. Secondary outcome of diet quality (kcal, carb, fat, protein) will be measured pre-post intervention via diet log. Exploratory outcomes of daily physical activity (steps, intensity), nightly sleep characteristics (quantity, quality, latency, efficiency), and daytime sleepiness and hunger.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Roasted, lightly salted, pistachio kernels (no shell)
Locations(1)
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NCT07340125