Blood Storage Related Mortality and Adverse Effects in Trauma Patients
Is Long-Term Blood Storage Related With Increased Mortality and Adverse Effects in Severely Injured Trauma Patients?
Kocaeli City Hospital
300 participants
Jan 17, 2026
OBSERVATIONAL
Conditions
Summary
The purpose of this retrospective study is to examine the following factors related to blood storage time in severely injured trauma patients who received large blood transfusions: 1. The effect of blood storage time on the patient's 28-day mortality rate. 2. The relationship between storage time and other health problems that the patient may develop (such as heart disease, vascular occlusion, respiratory failure, infection, and organ failure). For this purpose, patients aged 18-75 who were admitted directly from the scene of injury and received large transfusions at Jacksonville Shands Hospital between January 1, 2023, and October 1, 2025, will be included. Data will be obtained from hospital information systems and anesthesia records
Eligibility
Inclusion Criteria3
- Patients between 18-75 years of age,
- Injury Severity Score\>15 and have received massive blood transfusions in our hospital from 1 January 2015 to 31 December 2025
- The patients admitted because of trauma and undergoing surgery
Exclusion Criteria3
- Patients with known cardiac or vascular diseases such as heart failure or malignant hypertension, those under anticoagulant treatment
- Patients with known serious kidney (on dialysis), lung, liver diseases, those under anticoagulant treatment
- Super obese patients with body mass index (BMI) 50 or above
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Locations(1)
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NCT07341139