RecruitingNot ApplicableNCT07342530

Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy

Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry Guided Breathing Therapy


Sponsor

Stanford University

Enrollment

70 participants

Start Date

Mar 9, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to examine two early interventions, Written Exposure Therapy and Capnometry Guided Breathing, to reduce post-traumatic stress disorder (PTSD) symptoms in women after childbirth as compared to usual care.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria6

  • Age ≥18
  • Delivered a live infant within 5 days
  • Severe maternal morbidity or infant admitted to NICU
  • PCL-5 ≥28
  • English-speaking
  • Able to consent and participate

Exclusion Criteria4

  • Active psychosis or mania
  • Current suicidal crisis
  • Current suicidal intent or plan
  • Cognitive impairment preventing participation

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Interventions

BEHAVIORALWritten Exposure Therapy (WET)

Participants will complete 5 writing sessions. One 50-minute session will be held in the hospital before discharge, followed by four 50-minute sessions by secure video once a week. Sessions are delivered by a trained study therapist under licensed clinician supervision.

DEVICECapnometry-Guided Breathing Intervention (CGRI)

Participants will complete one 45-minute in-hospital training session using the device, which includes a tablet and breathing sensor. They will then practice guided breathing at home twice daily for about 17 minutes each time for 4 weeks, with weekly phone check-ins from study staff.


Locations(2)

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States

Stanford University

Palo Alto, California, United States

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NCT07342530


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