RecruitingNCT07345481

Stimulus Equivalence Learning in Acquired Brain Injury.

The Principle of Stimulus Equivalence Learning and Its Neuropsychological Correlates in Adults With Acquired Brain Injury (ABI).


Sponsor

Klimmendaal Revalidatiespecialisten

Enrollment

40 participants

Start Date

Jan 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

Stimulus Equivalence Learning (SEL) is a form of learning in which stimuli (such as words, pictures, or sounds) become linked to one another in memory, even though this specific connection has not been directly taught. In a typical SEL task, two relations are taught explicitly (A→B and A→C), and the untrained relation (B→C) is then tested. This indirect relation is not intentionally or consciously learned and is considered a form of implicit learning. The principle of stimulus equivalence learning is still rarely applied in cognitive rehabilitation after acquired brain injury (ABI), with the exception of a few small (N=1) treatment studies that have shown positive effects. However, it remains unclear to what extent ABI may affect the ability to acquire stimulus equivalence.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria1

  • ABI patients (>3 months post-injury), including stroke, traumatic brain injury, brain tumor, encephalitis, and out-of-hospital cardiac arrest (OHCA).

Exclusion Criteria2

  • Neurodegenerative disorders Severe psychiatric disorders (including suicidality) Insufficient command of the Dutch language Severe cognitive impairments, aphasia, or visual or hearing problems that make test administration impossible
  • An additional exclusion criterion for controls was any medical condition that could lead to cognitive impairment beyond normal aging, including stroke, TBI, brain tumor, or other forms of brain injury.

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Locations(1)

Klimmendaal Revalidatiespecialisten

Arnhem, Gelderland, Netherlands

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NCT07345481


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