A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

This study is checking how an investigational drug called MK-2828 behaves in people with severe kidney problems or who are on dialysis, compared to people with normal kidney function. When the kidneys aren't working properly, it can change how drugs are processed in the body, so researchers need to understand if dose adjustments are needed. **You may be eligible if...** - You have severe kidney disease (eGFR less than 30 mL/min) but are NOT on dialysis, OR - You have end-stage renal disease and are on regular outpatient hemodialysis (kidney dialysis) for at least 3 months - You are in generally good health apart from your kidney condition **You may NOT be eligible if...** - You have other significant illnesses that could affect how the drug is studied (for kidney disease participants) - You are healthy but have a history of significant heart, liver, kidney, blood, or neurological conditions (for healthy matched control participants) Talk to your doctor to see if this trial is right for you.